Debut of The Substance: Streaming Platforms for 2025

Four months after winning the Best Screenplay award at the 2024 Cannes Film Festival, where it earned a 13-minute standing ovation, Coralie Fargeat’s body horror satire The Substance hit US theaters. Since then, the film has garnered numerous awards and nominations, including five Oscar nods. Starring Oscar-nominated actors Demi Moore and Margaret Qualley, IGN’s 8/10 review described The Substance as "a sick, twisted, and squirm-inducing parable that critiques celebrity culture’s fixation on youth and beauty."

If you’re looking to stream The Substance online, here’s how and where you can watch it.

How to Watch The Substance Online

The Substance

Stream it on Prime Video or watch it on MUBI

The Substance is available exclusively on Mubi rather than Netflix or Hulu. Mubi requires a subscription but offers a seven-day free trial. If you prefer not to commit to another streaming service, the film is also available for rent or purchase on most digital platforms, including Prime Video and Apple TV+.

The Substance on Blu-ray

The Substance [4K UHD + Blu-ray + Digital]

Demi Moore delivers a standout performance as Elisabeth Sparkle, a former A-list celebrity who loses her role on a fitness TV show after being fired by studio head Harvey. Desperate for a fresh start, she turns to THE SUBSTANCE—a single injection that transforms her into the stunning, youthful Sue.
$42.98 | Save 42%
$24.96 at Amazon

Want to expand your horror collection? The Substance is now available on 4K Ultra HD. For more details about physical releases, check out our comprehensive guide to upcoming Blu-ray titles.

What Is The Substance About?

The Substance is a satirical body horror-thriller written and directed by Coralie Fargeat. Here is the official synopsis from Mubi:

Elisabeth Sparkle (Demi Moore), a once-famous actress past her prime, is offered a life-changing opportunity by a mysterious new drug. With just one injection, she is temporarily reborn as the beautiful, twenty-something Sue (Margaret Qualley).

The only condition? They must share the same body—alternating one week at a time. No exceptions. Sounds simple, right?

The Substance Cast

The Substance was written and directed by Coralie Fargeat. The film stars:

as Elisabeth SparkleMargaret Qualley as SueDennis Quaid as Harvey

The Substance Rating and Runtime

The Substance is Rated R for intense bloody violence, gore, graphic nudity, and strong language. The film has a total runtime of 2 hours and 20 minutes, including credits, and does not contain any post-credits scenes.